Equalizing
Equalizing is improving one eye instead of both eyes at the same time. It's done to reduce the diopter gap between two eyes, so that both eyes have a more similar or identical level of correction. It is recommended to do at least 2 spherical reductions before attempting to equalize. At which point you will alternate a monocular (one eye only) drop, with a binocular (both eyes) drop or better still, two binocular drops before another monocular drop. It is not recommended to do two monocular drops in a row. This approach should work for spherical and cylindrical reductions alike, and like all reductions should be done in the standard of .25 at a time; except sometimes it is possible to reduce cylinder more by using spherical equivalent.
Be mindful to maintain your diopter ratio for both normalized and differentials.
You may need to incorporate some patching through this process.